Senior Machine Learning Scientist (CA)
What We Do
We build AI models to enable smaller, faster, and more successful clinical trials.
About Altis Labs
Altis Labs is a computational imaging company focused on improving how oncology trials measure treatment benefit. Our core technology is IPRO, an AI model that generates patient-level outcome predictions directly from routine medical imaging data. Our global biopharma customers use IPRO to predict efficacy, navigate billion-dollar development decisions with confidence, and move their most promising therapies through Phase I–III trials faster. IPRO is trained on the industry’s largest real-world imaging, clinical, and outcomes database, containing over 210 million longitudinal images and more than one million patient-years of linked outcomes.
Our multidisciplinary team of AI scientists, clinicians, and business operators is on a mission to get the most effective treatments to patients sooner. We collaborate closely with academic medical centers and co-publish our results at top-tier medical conferences.
Altis is headquartered in Toronto, serves 6 of the top 20 global biopharmaceutical companies, and is backed by leading life sciences and technology investors.
What makes this role compelling:
- Unusually rich data: Access to large, diverse patient datasets with longitudinal outcomes across multiple cancer types
- Novel methodology: We're developing approaches that push beyond standard practices in medical imaging AI
- Multi-cancer generalization: Building methods that transfer across cancer types, not one-off solutions
Responsibilities & Expectations:
- Design and implement deep learning architectures for 3D volumetric medical imaging (CT, PET, MRI)
- Develop survival models that handle censored outcomes, competing risks, and the statistical nuances of time-to-event prediction
- Optimize training pipelines to efficiently process large-scale imaging datasets on cloud GPU infrastructure
- Collaborate with our ML team to establish best practices and push the state of the art
- Contribute to research publications and present findings at conferences
Qualifications:
- 7+ years of experience in machine learning, with substantial work in computer vision or medical imaging
- PhD in machine learning, computer vision, statistics, or a related field preferred; exceptional industry track record considered
- Deep expertise in 3D vision—experience with volumetric architectures (3D CNNs, Vision Transformers for 3D data, etc.)
- Strong foundation in survival analysis and time-to-event modeling (Cox models, deep survival models, competing risks)
- Proven ability to train large models efficiently at scale—you understand distributed training, memory optimization, and what it takes to iterate quickly on big data
- Proficiency with PyTorch and modern ML infrastructure
- Track record of impactful research (publications, deployed systems, or equivalent demonstrations of technical depth)
Nice to have:
- Experience with medical imaging foundation models or self-supervised learning on unlabeled imaging data
- Background in uncertainty quantification: calibrated predictions, conformal prediction, Bayesian deep learning
- MLOps experience: productionizing models, CI/CD for ML, model monitoring
- Familiarity with oncology, radiology, or regulated healthcare environments
Benefits:
- Competitive pay and generous equity participation
- Coverage for medical, vision, and dental insurance
- 4 weeks of vacation per year
About Altis Labs
Altis helps biopharma run faster and more successful clinical trials using AI models trained on the world's largest cancer imaging database.