Distributed Systems Engineer Jobs in San Francisco, California

26 open Distributed Systems Engineer jobs in San Francisco, California at 18 companies, including Thinking Machines Lab, Crusoe and OpenAI. Updated daily from company career pages.

Thinking Machines Lab

Crusoe

Aligning the future of computation with the future of the climate

OpenAI

OpenAI is an AI research and deployment company that conducts research and implements machine learning.

Discord

Discord is an online voice, video, and text communication platform designed for creating communities.

Anthropic

Anthropic is an AI safety and research company that focuses on increasing the safety of large-scale AI systems.

Mixpanel

Mixpanel is helping the world learn from its data by offering event analytics everyone can use

Figma

Figma is a design platform that develops web applications for interface design with offline features.

Baseten

Baseten is an AI infrastructure company that integrates machine learning into business operations, production, and processes.

Together AI

Together AI is a cloud-based platform designed for constructing open-source generative AI and infrastructure for developing AI models.

Inngest

Inngest is the developer platform for easily building reliable workflows with zero infrastructure.

Lightning AI

Lightning AI is the first operating system for AI. Build AI models and Lightning Apps (end to end ML systems).

Altruist

Altruist is a digital investment platform that offers commission-free trading and financial advice to individuals.

Ambience Healthcare

Ambience Healthcare is the leading AI operating system for healthcare organizations.

Meter

Meter builds internet infrastructure tailored for businesses, delivering secure and easily accessible networks.

Archil

The high-performance file system that connects AI to data

Cognition

Cognition is an applied artificial intelligence lab that focuses on reasoning and code.

Verse.ai

The most powerful AI platform for business conversations

Dedalus Labs

Compute substrate for AI agents

Updated 2026-10-11.