Principal Machine Learning Engineer Jobs in San Francisco Bay Area

123 open Principal Machine Learning Engineer jobs in San Francisco Bay Area at 54 companies, including Amazon, Snap and Mastercard. Updated daily from company career pages.

Amazon

Amazon is an e-commerce website for consumers, sellers, and content creators.

2 more open roles at Amazon

Snap

Snap operates as a privately-owned global camera company focusing on multinational technology and social media.

Mastercard

Mastercard is a technology company in the payments industry.

Cisco

Cisco develops, manufactures, and sells networking hardware, telecommunications equipment, and other technology services and products.

Microsoft

eBay

eBay is an online marketplace that connects a global network of buyers and sellers.

Palo Alto Networks

Anthropic

Anthropic is an AI safety and research company that focuses on increasing the safety of large-scale AI systems.

3 more open roles at Anthropic

Atlassian

4 more open roles at Atlassian

Hewlett Packard Enterprise

Hewlett Packard Enterprise is an edge-to-cloud company that uses comprehensive solutions to accelerate business outcomes.

Oura

Oura is a health technology company that makes and designs wellness wearable rings to track and improve sleep and performance.

Replit

Replit is a browser-based integrated development environment for cross-platform collaborative coding.

Qualcomm

Qualcomm designs, manufactures, and markets digital wireless telecommunications products and services.

2 more open roles at Qualcomm

Midjourney

Midjourney is a non-profit research lab that is investigating new thought mediums to improve the human species' inventive abilities.

ServiceNow

JP Morgan Chase

JP Morgan Chase is a global financial services provider that offers investment banking, asset management, treasury, and other services.

2 more open roles at JP Morgan Chase

Igneous

Igneous offers an unstructured data management solution giving data-centric enterprises visibility, protection, and data mobility at scale.

Marvell

Hippocratic AI

Hippocratic AI aims to develop the first Large Language Model (LLM) specifically designed for healthcare, prioritizing safety and accuracy.

Roblox

Roblox is an online gaming and entertainment platform that offers a shared digital experience that brings people together through play.

1 more open roles at Roblox

Updated 2026-10-11.