Principal Machine Learning Engineer Jobs in San Francisco, California

41 open Principal Machine Learning Engineer jobs in San Francisco, California at 21 companies, including Snap, Mastercard and Anthropic. Updated daily from company career pages.

Snap

Snap operates as a privately-owned global camera company focusing on multinational technology and social media.

Mastercard

Mastercard is a technology company in the payments industry.

Anthropic

Anthropic is an AI safety and research company that focuses on increasing the safety of large-scale AI systems.

3 more open roles at Anthropic

Atlassian

2 more open roles at Atlassian

Oura

Oura is a health technology company that makes and designs wellness wearable rings to track and improve sleep and performance.

Midjourney

Midjourney is a non-profit research lab that is investigating new thought mediums to improve the human species' inventive abilities.

Sygaldry Technologies

quantum-accelerated AI servers

OpenAI

OpenAI is an AI research and deployment company that conducts research and implements machine learning.

1 more open roles at OpenAI

Amazon

Amazon is an e-commerce website for consumers, sellers, and content creators.

Pinterest

Pinterest is a visual bookmarking tool for saving and discovering creative ideas.

Autodesk

Autodesk develops 3D design software for use in the architecture, engineering, construction, and media industries.

Datadog

Datadog offers monitoring and analytics for cloud-based workflows.

Docker

Docker’s platform helps millions of developers efficiently and collaboratively build, share, and run applications.

Perplexity AI

Perplexity AI is an AI-chat-based conversational search engine that delivers answers to questions using language models.

Elastic

Elastic builds software to make data usable in real time and at scale for search, logging, security, and analytics use cases.

DoorDash

DoorDash is a food delivery platform that connects customers with local and national business.

Tubi

Tubi is the world’s largest ad-supported video on demand (VOD) service. Available on Connected TV devices, Mobile, and the Web.

Bank of Montreal

Bank of Montreal is a financial services provider of retail banking, wealth management, and investment banking products and solutions.

Trulioo

Trulioo is an online verification company that operates a digital identity network deploying security and privacy standards.

Simbe Robotics

Simbe Robotics builds automation solutions for shelf auditing and analytics.

Updated 2026-10-10.