Systems Engineer Jobs in San Francisco, California

61 open Systems Engineer jobs in San Francisco, California at 33 companies, including Hewlett Packard Enterprise, Vercel and LangChain. Updated daily from company career pages.

Hewlett Packard Enterprise

Hewlett Packard Enterprise is an edge-to-cloud company that uses comprehensive solutions to accelerate business outcomes.

Vercel

Vercel's frontend cloud gives developers frameworks, workflows, and infrastructure to build a faster, more personalized web.

LangChain

LangChain enables developers to accelerate their LLM application workflows by overseeing the entire project lifecycle.

Harvey

Harvey is a generative AI company building the future of professional services.

Crusoe

Aligning the future of computation with the future of the climate

Redwood Materials

Redwood Materials is a battery recycling startup that makes electric vehicles and sustainable materials for circular supply chains.

HeartFlow

HeartFlow is a medical technology company that provides various methods of diagnosis and treatment of cardiovascular disease.

Sesame AI

Sesame AI is a technology company developing software and hardware products.

Applied Compute

OpenAI

OpenAI is an AI research and deployment company that conducts research and implements machine learning.

7 more open roles at OpenAI

Waymo

Waymo improves transportation by developing self-driving technology developed in Google’s labs.

Oracle

Okta

Okta is a management platform that secures critical resources from cloud to ground for workforce and customers.

Anthropic

Anthropic is an AI safety and research company that focuses on increasing the safety of large-scale AI systems.

Klaviyo

Klaviyo is an automation and email platform designed to help grow businesses.

Intercom

Intercom creates modern customer service software that redefines how businesses support their customers.

DoorDash

DoorDash is a food delivery platform that connects customers with local and national business.

Flexport

Flexport is a full-service global freight forwarder and logistics platform using modern software to fix the user experience in global trade.

Runway

Runway is an applied AI research company that builds the next generation of creativity tools.

Ramp

Ramp is a finance automation platform that helps businesses spend less time and money.

Updated 2026-10-10.